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End Stage Renal Disease (ESRD) patients on maintenance hemodialysis may have low plasma carnitine concentrations and an increased ratio of acylcarnitine/carnitine because of reduced intake of meat and dairy products, reduced renal synthesis and dialytic losses

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In the Prenatal THC/stress group, upregulated genes were enriched for startle response, dendritic spine development, and glutamate-receptor binding, whereas downregulated genes involved cellular respiration, plasma membrane receptor complexes, and integrin binding, indicating altered synaptic excitability and cellular energetics

10.1016/j.ijbiomac.2022.10.079 131 ShenY.LiuX.ShiJ.WuX

These tissue changes may affect medication absorption and cause visible skin changes

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