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The lack of functional GSTU13 resulted in enhanced disease susceptibility toward several fungal pathogens including Erysiphe pisi, Colletotrichum gloeosporioides , and Plectosphaerella cucumerina (Pislewska-Bednarek et al., 2018)

Additionally, the GTP-cyclohydrolase 1 (GCH1)-antioxidant tetrahydrobiopterin (BH 4 ) pathway is a key GPX4-independent system that regulates ferroptosis [48]

However, the story did not end there

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BRAF plays a vital role in the mitogen-activated protein kinases/extracellular signal-regulated kinases (MAPK/ERK) signaling pathway, which influences cell growth and proliferation (226)