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Providers should weigh discontinuation decisions carefully in these populations and discuss restart plans proactively if stopping is unavoidable
Current serotonin medications are aimed at increasing central 5-HT neurotransmission in the brain, and there are no approved indications for manipulating peripheral 5-HT, though peripheral 5-HT synthesis is being considered as a potential target for developing pharmacological agents in some disorders (8, 9)
Giacosa A, Guido D, Grassi M, et al
Enhanced intracellular reactive oxygen species by photodynamic therapy effectively promotes chemoresistant cell death
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Association between sleep disorders and constipation risk: a systematic review and meta-analysis
