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Blood levels stabilize at approximately 2x your weekly dose due to accumulation

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Nunes JM, Bizerra FC, Ferreira RC, Colombo AL (2013) Molecular identification, antifungal susceptibility profile, and biofilm formation of clinical and environmental Rhodotorula species isolates

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When comparing the prefusion and postfusion conformation, several structural changes in the domains are evident, alongside the rearrangement of the individual domains as a whole (Fig