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As the only cytochrome P450 enzyme involved in all known sterol biosynthetic pathways across eukaryotes, CYP51A1 performs a critical demethylation step that enables the formation of cholesterol in mammals and ergosterol in fungi
Research indicates that NSAIDs can inhibit key enzymes involved in glutathione recycling, limiting the bodys ability to replenish its antioxidant defenses
Effect of apigenin on tryptophan metabolic key enzymes expression in lipopolysaccharide-induced microglial cells and its mechanism
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Ann Neurol 52:771778 Klivenyi P, Kiaei M, Gardian G et al (2004) Additive neuroprotective effects of creatine and cyclooxygenase 2 inhibitors in a transgenic mouse model of amyotrophic lateral sclerosis
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