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Until a few years ago, the most effective strategy for sustained weight loss was surgery

Gut microbiome quantification

Unreconstituted lyophilized vials do not require cold chain storage, meaning they can travel at room temperature without concern

Methods This retrospective cohort study included adults with overweight or obesity and 1 pharmacy claim for semaglutide 2.4 mg or tirzepatide in the US Komodo Health database between June 4, 2021, and December 15, 2023

The following antibodies were used: phospho-S6K (Thr389), 4E-BP1, Cleaved-caspase-3, LC3A/B (Cell Signalling Technology, Beverly, MA, USA)

Understanding your patient population is key