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Nissen and Lincoff suspect that reluctance will erode over time as more of these types of medications get approved for weight loss, particularly if the SELECT and SURMOUNT-MMO trials result in indications for atherosclerotic CVD

This early timing points strongly toward the gastric emptying mechanism as the primary driver of initial thyroid function changes

Weeks 3 to 6: When Patients Notice the Waistline Shift By weeks three to six, the cumulative lipolytic effect on visceral fat begins to produce visible changes

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