Marchesini G, Brizi M, Bianchi G, Tomassetti S, Zoli M, and Melchionda N: Metformin in non-alcoholic steatohepatitis
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Is TB-500 safe for long-term use
PMC 4607138
Acta Paediatr Scand Suppl
For the majority of patients (75 to 85%), meaningful side effect resolution occurs by week 3 to 4 at each dose, and most side effects are nearly gone by month 3 to 4 of total treatment