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Cellular studies have shown that exogenous NAD + can impact mitochondrial activity, such as boosting Krebs cycle and the ETC, but also impair genomic DNA replication and induce DNA replication stress due to impairment of pyrimidine biosynthesis 118
et al., 2009)
They come from hormone changes that shift how your body stores fat, regulates appetite, and burns calories
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doi: 10.1186/s13054-015-1149-5 133 SinhaS.LinG.FerencziK
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