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48 Initial evaluation in healthy humans revealed that oral administration of Danuglipron produced a dose-dependent increase in systemic exposure bioavailability

doi: 10.1016/S0140-6736(21)01324-6 223 CefaluWTKaulSGersteinHCHolmanRRZinmanBSkylerJSet al

First introduced in Europe in the 1950s and approved by the U.S

Targeting the regulation of iron homeostasis as a potential therapeutic strategy for nonalcoholic fatty liver disease

It enhanced liver catalase and serum antioxidant capacity while reducing serum malondialdehyde and liver interleukin 1 beta and interleukin 6 expression

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