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Intracellular calcium homeostasis and its dysregulation underlying epileptic seizures
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Glycine is the other major conjugating amino acid in humans
GNE inhibition results in hyposialylation of IGF-1R Since the key function of GNE is epimerization and phosphorylation of precursors in the sialic acid biosynthetic pathway, absence of functional GNE would cause hyposialylation and affect sialylation of cell surface receptors 15,30
Melatonin mediates the bodys response to variations of natural light availability from indoor/outdoor exposure or to the change of seasons (winter to summer)
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