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Kiprov DD, Herskowitz A, Kim D, et al
The transmigration of immune cells across the BBB involves interactions with ECs, changes in endothelial transcellular and paracellular transport, and morphological alterations of the immune cells
However, like all research peptides, it must be used only in non-human laboratory settings , and should never be promoted or interpreted as a therapeutic product
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It was first isolated in 1977 by Swiss researchers Guido Schoenenberger and Marcel Monnier, who identified it in the cerebral venous blood of rabbits whose brains had been electrically stimulated to induce slow-wave sleep
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