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Nonclinical Observations Repeat-dose animal studies reported reduced food intake and body-weight changes consistent with GLP-1 receptor agonism Rodent studies identified dose-dependent thyroid C-cell hyperplasia and embryo-fetal toxicity at relevant exposures, informing laboratory hazard assessments

Factors that influence optimal maintenance dose include starting body composition, individual metabolic response, side effect tolerance, and research goals

Pinch the skin if appropriate Gently pinch a fold of skin between your thumb and forefinger to lift the subcutaneous tissue away from the muscle beneath

Pharmacology of GLP-1 RAs Endogenous GLP-1 is secreted from intestinal L-cells following oral nutrient intake

You should take BPC-157 consistently daily for up to 3 months, then give it a break for one month