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doi: 10.3389/fendo.2017.00280

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Notably, the Canagliflozin and Renal Events in Diabetes with Established Nephropathy Clinical Evaluation (CREDENCE) trial, the first dedicated kidney outcome trial evaluating canagliflozin in people with type 2 diabetes mellitus and CKD, demonstrated a substantial reduction in the risk of kidney events [46]

1g) 51 and conducted downstream analyses

Treat estimated levels and patterns as context, not diagnosis or dosing guidance

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