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Recent studies have revealed that exosomes derived from iPSCs can deliver protective miRNAs, including miR-21 and miR-210, which suppress the expression of pro-apoptotic proteins such as PDCD4 and Caspase-3 (Figure 1) ( Importantly, iPSCs undergo metabolic reprogramming under hypoxic conditions, shifting from oxidative phosphorylation to glycolysis

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Yang Y., et al

Second, it provides a steady, consistent drip of glutathione into the blood plasma over several hours

Immunocytochemical analysis confirmed that these newly formed spines were functional, showing similar percent correlations with presynaptic markers VGLUT1 and synapsin, and postsynaptic marker, PSD-95, as control-treated neurons