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Deactivation Mechanism of Glucagon-like Peptide-1/2 by Dipeptidyl Peptidase 4 Intestinal L-cells and K-cells release the physiologically active forms of GLP-1 and GIP, known as active GLP-1 amide and GIP, in response to oral glucose via increased cAMP (69)

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Approval Expectation: Under "Fast Track" or "Priority Review" designations often given to breakthrough metabolic therapies, an FDA approval decision is anticipated in late 2026 or early 2027

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