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Signs may include sharp, intense pain during injection, deeper aching sensation lasting hours or days, and increased soreness with movement of the affected limb

Some people might be more sensitive to changes: People with a history of depression or anxiety Those with a past eating disorder People using other medications that affect mood Patients with thyroid issues or hormone imbalances If this is you, talk with your doctor before starting a GLP-1 med

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However, there is also no cogent reason to avoid the combination, and the different mechanisms of retinol and peptides for skin care and anti-aging may complement their effects