Hypersensitivity reactions Serious hypersensitivity reactions, including anaphylaxis and angioedema, have been reported with semaglutide Avoid use in patients with known hypersensitivity to semaglutide and use caution in patients with a history of reactions to other GLP-1 analogs Semaglutide antibodies Semaglutide can induce an immune response that leads to the production of anti-semaglutide antibodies, and in some cases, these antibodies cross-react with endogenous GLP-1 In trials, 2.9% of Wegovy-treated patients developed anti-semaglutide antibodies, and of these patients, 56% had antibodies that cross-reacted with endogenous GLP-1
"So there are many possible reasons we're seeing signals that the trials may have missed." Overlooked effects Nearly half of the users reported one or more side effects
The most well-known syndrome associated with macroglossia is Beckwith-Wiedermann syndrome (BWS) [76]
This medication works by mimicking the action of a hormone called glucagon-like peptide-1 (GLP-1) in the body
Longer activity window Effects last 6 to 8 hours, sometimes longer
Once done breastfeeding, a woman, in consultation with her doc, can go back on semaglutideslowly