In the pancreas, activation stimulates glucose-dependent insulin secretion, meaning insulin is released only when blood glucose levels are elevated, which reduces the risk of hypoglycemia compared to some other diabetes medications

Top soluble fiber sources: Oats : 4g fiber per cup (cooked), the gold standard for gentle, effective fiber Chia seeds : 10g fiber per ounce, soak in liquid to form a gel that moves through the digestive tract smoothly Ground flaxseeds : 3g fiber per tablespoon, add to yogurt or smoothies Avocado : 10g fiber per avocado, plus healthy fats that aid absorption of fat-soluble vitamins Sweet potatoes : 4g fiber per medium potato, gentle and easy to digest when baked Berries : 3-4g fiber per cup, low glycemic, packed with antioxidants Beans and lentils : 6-8g fiber per half cup, introduce gradually Specific foods with natural laxative properties: Kiwi fruit : 1-2 daily has been shown in clinical studies to improve constipation, contains actinidin enzyme that aids digestion Prunes : 3-4 daily, contain sorbitol which draws water into the intestines Pears : High in sorbitol and fiber, gentle on the stomach One study-backed tip that many people on tirzepatide find helpful: start each morning with a glass of warm water followed by two kiwi fruits

Because these therapies often reduce appetite, focusing on nutrient-dense foods is essential to ensure the body receives vital vitamins and minerals from smaller portions
Once this period lapses, you feel less hungry, or feel your stomach turns full even before it actually gets filled with foods
Additionally, losing weight can lead to improved energy levels and better sleep quality
Your primary care provider or endocrinologist should review your baseline TSH and free T4 levels before starting GLP-1 therapy, and periodic monitoring during treatment ensures any levothyroxine dose adjustments are made promptly