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Modern Medicine for Obesity If you've been reading the Huddle for a while, you know I've covered GLP-1s from nearly every angletheir mechanism, their economics, their access barriers, and their adherence problems

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In a clinical trial comparing tirzepatide and semaglutide, people taking tirzepatide showed roughly 20 percent drops in weight in a similar amount of time, while people on semaglutide lost around 14 percent

Any excess gets excreted in the urine

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In the following sections, we will dive deeper into what semaglutide is, how Tylenol works, and what you should know before using them together