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N-Acetylcysteine (NAC) and its role in clinical practice management of cystic fibrosis (CF): a review

(2021) demonstrated that MOTS-c levels decline with age in both mice and humans, and that exogenous MOTS-c administration improved physical capacity in aged mice without observable toxicity over a 2-week treatment window [5]

Table 4: Post-treatment cognitive function test results, December 2023

genotypes carrying the C allele exhibited higher phenotypic values for GC and GIC, indicating a positive association with the C allele