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Upon differentiation these tNs extended axonal projections across both hemispheres, and showed evidence of myelination at early, intermediate, and fully compacted stages, as confirmed by EM

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Here we find increased proportion of pro-inflammatory and mesenchymal fibroblast subpopulations and senescent fibroblasts, and enhanced expression of senescence-associated secretory phenotype genes using single-cell RNA sequencing analysis, as well as elevated p16 protein and more -galactosidase-positive cells in keloids