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Hereditary intrinsic factor deficiency is caused by homozygous or compound heterozygous mutation of the CBLIF (cobalamin binding intrinsic factor) gene on chromosome 11q12.1 (168

We tailor the schedule based on your symptoms, diet, age, lab work if available, and any medications you're on, metformin, PPIs, or H2 blockers in particular

Safety vs

Systemic lupus erythematosus (SLE) and rheumatoid arthritis have been noted in case reports

The biggest differences are how they are administered, how often you need to take them, and how effective they are

Follow-up testing: Keep checking B12 levels and adjust treatment as needed, every 3-6 months