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Additionally, the activation of microglia and astrocytes in ALS leads to the production of ROS and pro-inflammatory cytokines, further exacerbating oxidative damage and motor neuron degeneration [170]
X Zhang, C Liu, J Guo & Y Song
Inhibition of this receptor reduces gliosis, protects axons, and improves clinical outcomes in preclinical MS models [430]
Male mice were treated with two doses of ADSP (400 and 800 mg/kg) and AFP (500 and 1000 mg/kg) daily for three weeks in their respective groups
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