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These canonical functions positioned DHODH primarily as a metabolic enzyme critical for nucleotide biosynthesis and cellular proliferation, before its more recent identification as a mitochondria-specific ferroptosis suppressor in select cancer contexts

Cysteamine and glutathione could also promote the production of pheomelanin rather than eumelanin

37 Metabolic reprogramming driving repair and regeneration Since around 2010s, the role of metabolic reprogramming in liver regeneration has become a focal point of research

When they fall out of balance, you start to feel the drag

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