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MDM2 was proven to ubiquitinate the IGF-1R and degraded it in a proteasome-dependent manner (Girnita et al, 2003), eventually leading to cell death

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In pediatric patients aged 6 to 23 months who received a single dose of 0.25 mg/kg cetirizine oral solution (mean dose 2.3 mg), the mean Cmax was 390 ng/mL

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Environmental microplastic and nanoplastic: exposure routes and effects on coagulation and the cardiovascular system