doi: 10.1161/CIRCULATIONAHA.118.036652 9 BrandtL
The main concerns include additive gastrointestinal effects (nausea, vomiting, diarrhoea), cognitive side effects from topiramate (difficulty concentrating, memory problems), and potential for excessive weight loss
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The "4-in-1" formulation appears to combine glutathione (known for its antioxidant properties), collagen (for skin elasticity), vitamin C (which supports collagen production), and garcinia cambogia