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Viene prodotta principalmente nel fegato e nei reni, a partire da lisina e metionina - due amminoacidi essenziali -, con laiuto della vitamina C e di alcune vitamine del gruppo B

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Elevated metallothionein expression in long-lived species mediates the influence of cadmium accumulation on aging

In tumor cells, a switch of glucose metabolism from aerobic glycolysis to oxidation leads to inhibition of proliferation and induction of caspase-mediated apoptosis 82