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Phase 2b clinical trials were completed in Australia testing the drug in 300 obese individuals
The levels of each liver health measurement before and after the study for each group are shown in the table below: For the researchers, patients with NASH who were treated with L -carnitine compared with patients who were treated with placebo have (a greater) improvement in (the markers for liver health) and suggest that L-Carnitine exerts its health effects by helping detoxify the liver
Drug Design, Development and Therapy , 9, 2485 2499
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This is mostly mediated by the Glucose Transporter Type 4 (GLUT4), which enables glucose absorption into cells
The current recommended management of NASH and NAFLD remains limited to lifestyle modification, vitamin E supplementation, and pioglitazone in selected patients
