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While effective in supplementing B12 levels, they are not derived from natural food sources and are formulated to mimic the active forms of B12 found in the body

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Due to their similar structures, both hCG and LH bind to the same LHCGR receptor on Leydig cells, but hCG does so with greater affinity, preferentially inducing cAMP and increasing intracellular Ca, upregulating genes that code steroidogenic enzymes