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By age 60, those levels fall to roughly 80 ng/mL a decline that closely tracks the slowing of wound healing, skin thinning, and reduced regenerative capacity observed with aging

Comparison of empagliflozin and glimepiride as add-on to metformin in patients with type 2 diabetes: a 104-week randomised, active-controlled, double-blind, phase 3 trial

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Clinical protocols would require dosing windows linked to chemotherapy cycles and fertility treatments

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Klaassen CD, et al