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Beyond SELECT's findings in people without diabetes, semaglutide has demonstrated cardiovascular benefits across diverse patient populations, including those with type 2 diabetes and varying degrees of heart failure

GLP-1 Statistics 2026: What the Head-to-Head Data Shows A balanced look at the largest real-world comparisons between metabolic and bariatric surgery and GLP-1 medications weight loss outcomes, cost, durability, and why the two are increasingly discussed as options along the same care pathway rather than competitors

It shows that members who used the Noom GLP-1 Companion app most frequently achieved greater weight lossand a higher rate of medication program persistencecompared with less-engaged peers

Even comparing Retatrutides Phase 2 results against Wegovys best available data, the gap is substantial