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At the skin level, GHK-Cu stimulates the production of type I, III, and V collagen by dermal fibroblasts, as well as the synthesis of proteoglycans (decorin) and glycosaminoglycans

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However, EMS lesions inherently exhibit impaired mitophagy, leading to the persistent accumulation of dysfunctional mitochondria and increased ROS production

Association of reactive oxygen species levels and radioresistance in cancer stem cells