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Distinct changes in endosomal composition promote NLRP3 inflammasome activation

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That broader medical case is part of the reason why the World Health Organization added GLP-1 drugs to its essential medicines list last September, a model list of medicines it recommends countries make widely available through their health systems

Rosen LS et al

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Patients with electrolyte abnormalities or those experiencing significant gastrointestinal fluid losses also warrant closer monitoring