No obstante, se han descrito eventos menos frecuentes, pero potencialmente graves como pancreatitis, enfermedad biliar y obstruccin intestinal (Ver tabla 1) Recomendaciones para los Estados Miembros En la alerta epidemiolgica, la OPS explica que los productos mdicos no registrados, subestndar y falsificados representan una amenaza para la salud pblica
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Individuals at higher risk include older adults with reduced stomach acid production, people with gastrointestinal conditions affecting absorption, strict vegans, and those taking medications like metformin or proton pump inhibitors
Liraglutide stands out for having the strongest direct evidence of platelet inhibition, the controlled study showing 54% reduction in thromboxane-induced aggregation
Conflict of interest The authors have no conflicts of interest to declare that are relevant to the content of this article
But the proposed approach, outlined in the journal Molecular Metabolism by some of the most well-known scientists in the field, is likely to stir controversy, as it challenges a central notion underpinning not just the development of approved obesity products but also next-generation versions