Johns wort, as it can interact not only with antidepressants, but also with cardiovascular medications, like anticoagulation and anti-arrhythmic drugs
Williams SB, Cusco JA, Roddy MA, Johnstone MT, Creager MA
These include nausea, vomiting, diarrhoea, abdominal pain, and constipation, which typically occur during dose initiation or escalation and often diminish over time as the body adjusts to the medication
Jeong et al., 2013
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