Heartburn and reflux may respond to avoiding trigger foods (spicy, acidic, fatty items), eating smaller portions, remaining upright after meals, and elevating the head of the bed at night
pubmed.ncbi.nlm.nih.gov Aronne LJ, Horn DB, le Roux CW, et al
The missed dose window is three days, shorter than both semaglutide and tirzepatide
Common adverse events and side effects Tirzepatide may cause common side effects in irritable bowel syndrome, such as diarrhea, constipation, nausea, vomiting, upper abdominal discomfort, decreased appetite, and abdominal pain
Zarate D, et al
Practical steps that help: Start on the lowest dose (2.5 mg) and increase gradually Eat a diet based on whole foods, eat 3 balanced a meals a day, and consider protein-rich snacks in between meals if needed Spread fat intake across meals rather than having a lot in one sitting Stay well hydrated, especially if youre experiencing looser stools Keep a brief food diary if symptoms flare up, to identify triggers If diarrhoea persists rather than easing as your body adjusts, ask your GP about bile acid diarrhoea specifically