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A Danish study examining 424,152 persons with type 2 diabetes found patients exposed to weekly semaglutide had 2.19 times higher NAION risk, with Denmarks annual first-time NAION cases rising from 67.6 to 148 since Ozempics 2018 introduction

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Subcutaneous sites include the abdomen and outer upper arms

Proton pump inhibitors and similar medications that lower stomach acid might decrease the absorption of vitamin B12 from food, but this is less of a concern when receiving B12 injections because they bypass the digestive system entirely