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The American Diabetes Association (ADA) Standards of Care emphasize that diabetes is a progressive condition requiring ongoing pharmacological management in most patients, and discontinuing effective therapy typically results in deterioration of glycemic control

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And, as critics have pointed out over the years, by elevating just one, two, or at most, three researchers, the Nobels distort the history of science by personalizing discoveries that are truly made by groups of individuals. That reality hangs heavy especially over a decision about GLP-1 and other gut-hormone based drugs, given how much additional science had to be done to convert the hormones to effective, and then even more effective, drugs

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doi: 10.1200/jco.2021.39.15_suppl.tps597

Trends Mol Med 2005