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Subsequent work by Heffernan and coworkers (2001) confirmed the peptides effects in obese mouse models, with chronic administration associated with reduced body weight gain and decreased adiposity without concurrent changes in food intake

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Kiyoshi Okada, Hiroyuki Tanaka, Ko Temporin, Michio Okamoto, Yusuke Kuroda, Hisao Moritomo, Tsuyoshi Murase, Hideki Yoshikawa, Methylcobalamin increases Erk1/2 and Akt activities through the methylation cycle and promotes nerve regeneration in a rat sciatic nerve injury model, Experimental Neurology, Volume 222, Issue 2, April 2010, Pages 191-203 Tanaka, H

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