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Its first registrational Phase 3 obesity trial has confirmed weight loss outcomes that approach those previously achievable only through bariatric surgery, with meaningful cardiometabolic improvements alongside

A washout interval of 2 to 4 weeks was maintained between each arm of the crossover to minimize potential carryover effects

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If methylation is sluggish (often for genetic reasons) or the body doesn't have enough nutrients (including vitamin B12 and folate) to turn the methylation cycle, the body can't make enough glutathione