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doi: 10.3390/agriculture6020023 265 RackovaL.FirakovaS.KostalovaD.StefekM.SturdikE.MajekovaM
Therapies enhancing GSH could become a cornerstone to reduce severity and fatal outcomes of inflammatory diseases and COVID-19 and increasing GSH levels may prevent and subdue these diseases
Furthermore, redox modulation augmented by increased glutathione synthesis from glutamine was reported to be the mechanism of resistance to gemcitabine in pancreatic cancer cells 16
Mitochondrial GSH import by SLC25A39/40 is necessary for maintaining steady state levels of iron-sulfur clusters
Exposure to viruses, bacteria, radiation, environmental toxins, and pollution may deplete glutathione levels, resulting in a buildup of free radicals, which are unstable atoms that can be extremely harmful to the body
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