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Cells were cultured at 37 C with 5% CO 2 and subpassaged using a 1-in-4 dilution when a confluency of approximately 80% was reached

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W., Moss, D

10.1016/j.freeradbiomed.2012.02.043 Summary Keywords lapatinib, epileptic seizures, neuroprotection, ferroptosis, lipid peroxidation, glutathione peroxidase 4 Citation Jia J-N, Yin X-X, Li Q, Guan Q-W, Yang N, Chen K-N, Zhou H-H and Mao X-Y (2020) Neuroprotective Effects of the Anti-cancer Drug Lapatinib Against Epileptic Seizures via Suppressing Glutathione Peroxidase 4-Dependent Ferroptosis

Sci Rep 13 , 11513

On the basis of the type of metal ion required as cofactor by SOD, various forms of the enzyme exist.23, 24 The metal ions which are normally bound by SOD are iron (Fe), zinc (Zn) copper (Cu) and manganese (Mn)