A 2025 systematic review of the compound identified only 36 total studies, 35 of which were conducted on animals and just one single study (with a sample size of 12!) conducted on humans
Key Takeaway: The effectiveness of a supplement is determined by its bioavailabilitythe amount your body can actually absorb and userather than just the dose on the label
It circulates in your blood plasma, shows up in your saliva, and appears in your urine
Comparing the former version of these documents and the 2026 updated ones, the major changes are: Further examples or clarifications have been added to the following substance classes to help athletes and their entourage better identify prohibited substances: S1
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Dietary Reference Intakes for Vitamin C, Vitamin E, Selenium, and Carotenoids