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B12 shots supply vitamin B12 as methylcobalamin or cyanocobalamin, typically given intramuscularly into the deltoid, supporting red blood cell formation, myelin and nervous system health, and the metabolism of homocysteine, a process that can falter with vegan diets, malabsorption, or medications like metformin

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[25] Supplementation with vitamin B 12 during conditions of deficiency restores the intracellular level of cobalamin and maintains a sufficient level of the two active coenzymes: methylcobalamin and adenosylcobalamin