IECs detect antigens, secrete antimicrobials, and modulate immune responses, while immune cells regulate IEC-derived cytokines (212, 213)
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The ABCDE rule, used for skin melanoma, also works for mouth lesions: A: Asymmetry B: Border irregularity C: Color variation D: Diameter increase E: Evolving Going to the dentist regularly is key for catching it early
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