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Patients deserve better When it comes to obesity and these revolutionary new drugs (GLP1s+), we have to hold two competing ideas simultaneously
Chronic or repeated HPA axis stimulation raises legitimate concerns, as sustained cortisol elevation is associated with insulin resistance, altered body composition, bone loss, immune modulation, and cardiovascular effects
Telehealth prescribing of GLP-1 medications is rapidly reshaping how diabetes and weight management care is delivered
GLP-1 receptor expression in human tumors and human normal tissues: Potential for in vivo targeting
Preclinical studies have also revealed that dual agonists of GLP-1R and glucose-dependent insulinotropic polypeptide receptor (GIPR) have synergistic anti-inflammatory and neuroprotective effects, suggesting the potential advantages of multitargeting strategies (Yuan et al., 2024)
In particular, we observed that the -1 subcluster expressed low levels of ARX , IRX2 , CRYBA2 , ALDH1A1 , and TM4SF4
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