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Dry age-related macular degeneration: mechanisms, therapeutic targets, and imaging
Insurance Coverage: FDA-approved medications may be covered by insurance (though coverage for weight loss is limited)
Upon its secretion from the gut, GLP-1 activates GLP-1Rs located on the vagus nerve afferents, which leads to vagal glutamatergic excitation of PPG expressing neurons in the NTS [30]
While the medication has a well-documented side effect profile dominated by gastrointestinal symptoms, nosebleeds are not recognized as an established adverse effect in FDA prescribing information or clinical trial data
17 These medications may also lead to significant savings in healthcare costs over time, with a JAMA study showing that losing as little as 5% of body weight could translate into an 8% savings in healthcare costs for individuals each year
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