These changes create NDP--MSH (Nle4, D-Phe7--MSH), which is approximately 100-1000 times more potent than native -MSH at the MC1R receptor and is resistant to enzymatic degradation
Kristensen, P
Grases F, Prieto RM, Gomila I, Sanchis P, Costa-Bauza A
MCT helps with fatty acids lower gut pH, creating an environment less favorable for fungal overgrowth and caprylic acid enhances the activity of other antifungals (both natural and pharmaceutical), making resistant strains more susceptible
More specifically, the researchers posited that the peptide may have enhanced the expression of Ki-67 and CD98hc that are less intensively synthesized during cell aging. Epithalon also seemed to inhibit the activity of Caspase-3, a crucial enzyme believed to facilitate apoptosis (programmed cell death)
The dosing intervals of salmeterol have been changed to avoid potential ergogenic effects, though the maximum daily delivered dose remains the same