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537 HDAC-1 recruited by ATF6 inhibits SREBP2-mediated gene transcription, contributing to glucose homeostasis
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To test the accuracy of the developed model, the model predictions were validated against four independent datasets with different PO doses of metformin hydrochloride - 250mg dose dataset from Chung [36], 500mg dose dataset from Gusler [37], 750mg dose dataset from Wen [38] and a 500mg multiple dose dataset from El Messaoudi [39]
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